Will Shortz had always thought of himself as pretty healthy. The crossword editor for the New York Times and puzzle master of Weekend Edition Sunday on National Public Radio (NPR) worked out daily, didn't smoke or drink, and had no significant family history of heart disease.
He did have one worry, though. For years he'd had high blood pressure, with an upper (systolic) reading of 160 or even higher. After an appointment with his doctor in December 2023, Shortz changed his diet in an effort to reduce his sodium intake and lower his blood pressure. He cut out his daily can of soup at lunchtime and avoided eating at restaurants with sodium-packed menus. “A single entrée at many of the restaurants we frequented can have more than 100 percent of the suggested daily sodium intake,” Shortz says.
Changing his eating habits was a good start, but Shortz's hypertension likely played a role in what happened on February 4. Shortz was in his home office in Pleasantville, NY, pondering the next Times crossword puzzle, when he leaned to his left and suddenly realized he couldn't lean back to the right. “I had drool coming out of the left side of my mouth,” says the 72-year-old. “I knew immediately that I was having a stroke and would have to go to the hospital.”
Still in a T-shirt and shorts from playing table tennis (his other great passion), Shortz knew he'd need to put on long pants to go to the hospital, since it was February in New York. He managed to stand, walk into the bedroom, and put on the pants. Then he went to the bathroom: “I realized I couldn't flush the toilet, because my left side had become incapacitated. I couldn't use my left arm and leg at all. I sort of crumpled to the floor.”
For the next several minutes, he lay in the bathroom desperately trying to figure out what to do, unable to get on his hands and knees to crawl. His phone was still in his office. “It took me about 15 minutes to squirm my way back into the office, get my phone, and call my partner,” Shortz says. “He was there within three minutes.”
By the time the ambulance came, Shortz's initial symptoms had improved marginally. His three-story home sits on a hill with many steps down to the street, and he was able to stand up mostly on his own and walk almost 20 steps from the second floor to the street. But as he was waiting to be evaluated at Northern Westchester Hospital, Shortz's speech became slurred—he was having a second, larger stroke. After a CT scan of his brain confirmed the diagnosis, Shortz was given an intravenous thrombolytic medication designed to dissolve blood clots that cause acute ischemic stroke, restoring blood flow to the brain and minimizing the risk of damage.
It has long been known that “time is brain” when it comes to stroke, and the guidelines from the American Heart Association stress that eligible stroke patients should receive IV thrombolysis as soon as possible, ideally within three to four and a half hours of the stroke. In Shortz's case, the IV clot-busting therapy relieved the blockage that had caused the second stroke, but he also experienced mild bleeding in his brain, the most serious complication associated with the treatment.
“The initial trials of these drugs back in the 1990s found a 6.1 percent risk of symptomatic hemorrhage, but over time many things have improved with care after a stroke, so now we believe the overall risk of hemorrhage is about 3 percent,” says Amrou Sarraj, MD, director of the Cerebrovascular Center and Comprehensive Stroke Center at University Hospitals Cleveland Medical Center.
Although Shortz's bleeding resolved after a day of close monitoring with CT scans, he had to spend 10 days in the intensive care unit. “All things considered, it could have been worse,” he says.