What are the causes and risk factors of stroke?
Stroke risk is shaped by a mix of health, lifestyle, and environmental factors. The encouraging news is that many strokes can be prevented. Up to 80% of strokes are linked to risk factors that can be treated, changed, or controlled, including:
- High blood pressure
- High cholesterol
- Diabetes
- Atrial fibrillation (irregular heartbeat)
- Carotid artery disease
- Cigarette smoking
- Peripheral artery disease
- Heart failure
- Sickle cell anemia
- Poor diet
- Physical inactivity
- Obesity
These risk factors often overlap and build over time, which makes early awareness and prevention especially important.
Some stroke risk factors cannot be changed:
- Age: Stroke risk increases with age. After age 55, the chance of having a stroke roughly doubles with each passing decade.
- Sex: Stroke affects people of all genders, but women are diagnosed more often than men and are more likely to die from stroke. Pregnancy and certain hormone therapies can also raise stroke risk for some women.
- Race and ethnicity: In the United States, Black people are nearly twice as likely to have a first stroke. This is partly because rates of high blood pressure, diabetes, and obesity are higher in this group. Hispanic Americans also face elevated risk, and both Black and Hispanic people are more likely to die after a stroke than White people.
- Family history: Your risk may be higher if a parent, grandparent, brother, or sister has had a stroke. In rare cases, stroke can also be linked to inherited conditions.
- Prior stroke, TIA, or heart attack: If you’ve already had a stroke, transient ischemic attack (TIA), or heart attack, your risk of stroke is higher. A TIA, sometimes called a mini-stroke, causes stroke-like symptoms that go away within 24 hours, but it’s still an important warning sign.
Research suggests that differences in stroke risk between different demographic groups are caused mainly by differences in what’s called structural and social determinants of health, not genetics alone. These determinants are the conditions in which we’re born, grow, live, and work. They include our life experiences, access to timely care, and greater risk for other health conditions.